Friday, 1 May 2009

Hind Swaraj

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Hind Swaraj or Indian Home Rule is a small tract written by Gandhi in 1908. Gandhi had been living in South Africa for some years, had been to India on a visit, and on the voyage back to South Africa from London he penned this work in less than ten days, writing with his left hand when his right hand started giving him some pain. Hind Swaraj appeared first in installments in the pages of Indian Opinion, a newspaper founded and edited by Gandhi, and in 1909 was published as a book, though it was proscribed at once by the Government of Bombay. Less than 100 pages long, and comprised of twenty short chapters, Hind Swaraj is cast in the form of a dialogue between Gandhi, who is called "The Editor", and his interlocutor, known as "The Reader." Some readers might be reminded of the Socratic dialogues, where Socrates has by far the greater number of lines; his interlocutors appear as sophists. Others will think, perhaps, of the Upanishadic dialogues, while yet others might think of Hind Swaraj as a Sunday school catechism, where matters of ‘truth’ and ‘doctrine’ are put in the form of questions and answers.






As Gandhi was to observe in a foreword which he called "A Word of Explanation", he had in London come into contact with Indian "anarchists" or, in the language of the Indian government, "extremists", and had encountered these people in India as well. While struck by their "bravery", Gandhi thought the "zeal" of these extremists, who sought to procure India’s independence through the use of violence and techniques of terror, including political assassination and bombing campaigns, "misguided". For over a decade, Gandhi had been experimenting with non-violent resistance in South Africa, and he held firmly to the view that India was especially equipped to show the way out of violence through the higher law of non-violent resistance. Gandhi thought of Hind Swaraj as a book that could be "put into the hands of a child. It teaches the gospel of love in place of that of hate. It replaces violence with self-sacrifice. It pits soul force against brute force" (p. 16).





However, it is not for this reason alone that Gandhi wrote Hind Swaraj, and indeed its afterlife suggests that it is seldom read as a treatise on non-violence. Over the remaining forty years of his life, Gandhi would continue to write on non-violence, and his later writings have eclipsed Hind Swaraj in this respect. But if Hind Swaraj occupies a seminal place in Gandhi’s oeuvre, and can even reasonably be described as one of the most critical documents of the twentieth-century, it is because in this work he initiated what he himself described as "a severe condemnation of ‘modern civilization" (p. 16). Gandhi inaugurated the most far-reaching critique of modernity that one can imagine, and though it must have struck the preponderant number of his contemporaries as an absurd treatise, Hind Swaraj strikes the reader of late modernity as a work of extraordinary prescience and insight. All too often Hind Swaraj has been read as a denunciation of the West (qua West), but this reading is nowhere substantiated by the text. Throughout, Gandhi remains clear that the replacement of white rulers by brown rulers would be of little consequence to the people if the new set of rulers governed by the same principles, with the same objectives, and with a similar commitment to principles of modern civilization. As he put it with characteristic forthrightness, addressing his imaginary interlocutor, "we want English rule without the Englishman. You want the tiger’s nature, but not the tiger; that is to say, you would make India English. And when it becomes English, it will be called not Hindustan but Englistan." As he adds, pointedly: "This is not the Swaraj [freedom, self-rule] that I want" (p. 30). Doubtless, Western civilization was already largely synonymous with modern, industrial civilization: to this extent, Hind Swaraj can be read as a critique of the West. But Gandhi remained unequivocally bound to the view that India had been grounded into submission not so much by the British as by modern civilization; it is the glitter of the modern world that seduced India and rendered it captive. As he wrote, in a chapter entitled "Why was India Lost?", ""The English have not taken India; we have given it to them. They are not in India because of their strength, but because we keep them" (p. 38).





In Hind Swaraj, Gandhi launched into a ferocious critique of the "parasitic" professionals who staff modern society, particularly doctors, engineers, lawyers, and the like. He gave it as his opinion that sometimes "quacks are better than highly qualified doctors"; as for doctors trained in modern, allopathic medicine, Gandhi observed that "for the sake of a mistaken care of the human body, they kill annually thousands of animals. They practise vivisection" (pp. 59). Lawyers existed to "advance quarrels instead of repressing them" (p. 55). These and numerous other similar sentiments which crowd the pages of Hind Swaraj continue to be profoundly embarrassing to modernizing Indians, and Gandhi’s own contemporaries predicted that Hind Swaraj would soon be forgotten, repudiated by Gandhi himself. Gandhi’s own ‘mentor’, the political leader Gokhale, opined that Gandhi would consign Hind Swaraj to the dustbin of history, but Gandhi affirmed in 1921, and again in 1938, that he saw no reason to retract anything he had written in Hind Swaraj. There seems even less reason today to view Hind Swaraj as a merely Luddite or romantic document: in its ecological wisdom alone, and in its profound sense that there must be limits to human consumption, wants, and addiction to technological solutions, it remains an enduring and endearing work. Hind Swaraj is the indispensable work in the Gandhian canon.

Enrique Iglesias - Wish I Was Your Lover lyrics

Wish I Was Your Lover




You know I got this feeling that I just can't hide

I try to tell you how I feel

I try to tell you but I'm me

Words don't come easily

When you get close I share them



I watch you when you smile

I watch you when you cry

And I still don't understand

I can't find the way to tell you



I wish I was your lover

I wish that you were mine

Baby I got this feeling

That I just can't hide



Don't try to run away

There's many things I wanna say

No matter how it ends

Just hold me when I tell you



I wish I was your lover

I wish that you were mine

Baby I got this feeling

That I just can't hide



I wish I was your lover

I wish that you were mine

Baby I got this feeling

That I just can't hide



Oh I need is a miracle

Oh baby all I need is you

All I need is a love you give

Oh baby all I need is you

Baby you



I wish I was your lover

I wish that you were mine

Baby I got this feeling

That I just can't hide



I wish I was your lover ( I wish I was your lover)

I wish that you were mine

Baby I got this feeling

That I just can't hide



I wish I was your lover

I wish that you were mine

Baby I got this feeling

That I just can't hide



Just wanna be your lover

Just wanna be the one

Let me be the lover

Let me be the one

Yeah Yeah

Wednesday, 29 April 2009

Control of Genes




Control of Genes


Even simple organisms such as bacteria have as many as 3000 genes, producing protein products such as enzymes, cell wall components, building proteins, ribosomal proteins and many others. During a typical cell cycle a bacterial cell may have to make energy releasing proteins all the time, DNA synthesis proteins only during DNA replication, sugar digesting enzymes when it encounters sugar in its environment, and cell wall proteins only when it is about to grow and enlarge. Different proteins are needed at different times, some constantly but many only at specialized moments in the life of the bacterial cell. It would be both wastefull and inefficient to make all proteins continuously. The cell, therefore, needs some method of controling when and where these many different proteins are made

Bacterial Genes

Francois Jacob and Jacques Monod were the first scientists to successfuly investigate how cells control the production of proteins. They used bacteria (because of their simplicity) and developed a model of how these types of cells regulate their genes in response to changes in their environment. Bacteria are opportunists and respond quickly to new sources of food or the presence of dangerous chemicals. Their method of genetic regulation allows them to adapt very rapidly to to what is going on around them.

Jacob and Monod studied how bacteria respond to the sudden appearance of a sugar (called Lactose) in their growth medium. To digest this sugar the cells must make an enzyme called Beta-galactosidease. Since Lacatose sugar is rare, and not always available, it would be wasteful to make this specialized enzyme when it was not needed, so most bacterial cells do not make it until needed.


These scientists discovered that the sudden appearance of Lactose sugar cause the bacterial cells to turn on transcription (making mRNA) of the gene for the enzyme. This type of control of a gene is called transcriptional control, and turned out to be one of the major ways all cells control their genes and the production of proteins.

Enrique Iglesias - Just Wanna Be With You Lyrics

Monday night, and I feel so low,


I count the hours, but they go so slow.

I know the sound of your voice, can save my soul.

City lights, the streets are gold.

Looked down my window to the world below.

Move so fast, but it feels so cold

And I am all alone,

Don’t let me die, I’m losing my mind,

Baby, just give me a sign.



And now that you’re gone,

I just wanna be with you.

(Be with you)

And I can’t go on, I wanna be with you.

Wanna be with you..



I can’t sleep, I’m up all night.

Through these tears, I try to smile.

I know, the touch of your hand, can save my life.

But don’t let me down, come to me now,

I got to be with you some how.



And now that you’re gone,

I just wanna be with you.

(Be with you)

And I can’t go on, I wanna be with you.

(Be with you)

Wanna be with you.



Don’t let me down,

Come to me now.

I got to be with you some how.

And now that you’re gone,

Who am I without you now?



I can’t go on, I just wanna be with you.

And now that you’re gone,

I just wanna be with you.

(Be with you)

And I can’t go on,

I wanna be with you..

(Be with you)

Wanna be with you..



(Now that you’re gone)

Just wanna be with you..

And I can’t go on,

I wanna be with you.

Oh..

Just wanna be with you, just wanna be with you. (Fade)

Tuesday, 28 April 2009

Enrique Iglesias - Do You Know (Ping Pong Song) lyrics

Enrique Iglesias - Do You Know (Ping Pong Song) lyrics

Do You Know (Ping Pong Song)




DO YOU KNOW



Do you know?

Do you know?



Do you know what it feels like loving someone that's in a rush to throw you away?

Do you know, do you know, do you know, do ya?

Do you know what it feels like to be the last one to know the lock on the door has changed?



If birds flying south is a sign of changes

At least you can predict this every year

Love, you never know the minute it ends suddenly

I can't get it to speak

Maybe if I knew all the things it took to save us

I could fix the pain that bleeds inside of me

Look in your eyes to see something about me

I'm standing on the edge and I don't know what else to give.



Do you know what it feels like loving someone that's in a rush to throw you away?

Do you know, do you know, do you know, do ya?

Do you know what it feels like to be the last one to know the lock on the door has changed?



How can I love you?

How can I love you?

How can I love you?

How can I love you?

If you just don't talk to me, babe.



I flow through my act

There's a question: Is she needed?

And decide all the man I can ever be.

Looking at the last 3 years like I did

I could never see us ending like this.



(Do you know?)



Seeing your face no more on my pillow

Is a scene that's never ever happened to me.



(Do you know?)



But after this episode I don't see

You could never tell the next thing life could be



Do you know what it feels like loving someone that's in a rush to throw you away?

Do you know, do you know, do you know, do ya?

Do you know what it feels like to be the last one to know the lock on the door has changed?



Do you know what it feels like loving someone that's in a rush to throw you away?

Do you know, do you know, do you know, do ya?

Do you know what it feels like to be the last one to know the lock on the door has changed?



(Do you know?)

(Do you know?)

(Do you know?)

(Do you know?)



Do you know what it feels like loving someone that's in a rush to throw you away?

Do you know, do you know, do you know, do ya?

Do you know what it feels like to be the last one to know the lock on the door has changed?



Do you know what it feels like loving someone that's in a rush to throw you away?

(Do you know how it feels?)

Do you know what it feels like to be the last one to know the lock on the door has changed?

(Do you know how it feels?)



(Do you know? Do you know? Do you know? Do you?)

(Do you know? Do you know? Do you know? Do you?)

Wednesday, 22 April 2009

Enrique Iglesias - Tired Of Being Sorry lyrics

Enrique Iglesias - Tired Of Being Sorry lyrics


Tired Of Being Sorry




I don't know why

You want to follow me tonight

When in the rest of the world

With you whom I've crossed and I've quarreled

Let's me down so

For a thousand reasons that I know

To share forever the unrest

With all the demons I possess

Beneath the silver moon



Maybe you were right

But baby I was lonely

I don't want to fight

I'm tired of being sorry



Chandler and Van Nuys

With all the vampires and their brides

We're all bloodless and blind

And longing for a life

Beyond the silver moon



Maybe you were right

But baby I was lonely

I don't want to fight

I'm tired of being sorry

I'm standing in the street



Crying out for you

No one sees me

But the silver moon



So far away – so outer space

I've trashed myself – I've lost my way

I've got to get to you got to get to you



Maybe you were right

But baby I was lonely

I don't want to fight

I'm tired of being sorry

I'm standing in the street

Crying out for you

No one sees me

But the silver moon

(lalalala till end)

Maybe you were right

But baby I was lonely

I don't want to fight

I'm tired of being sorry

I'm standing in the street

Crying out for you

No one sees me

But the silver moon

Tuesday, 21 April 2009

Gene Regulation

Gene Regulation

The Operon





The Operon


 
Four regions of DNA control the production of a protein such as the enzyme Beta-galactosidease;

 
  •        a structural gene that holds the codons for the amino acid sequence found in the enzyme.
  •        an operator region right in front of the structural gene.
  •        a promotor region where the RNA making enzyme will bind to the DNA.
  •        a regulator gene which has a role in controling the transcription from the structural gene.

 
The combined region of the operator and structural gene is called an operon.

Summary :

Many genes are ....


... normally blocked by the action of a repressor protein. This prevents the RNA polymerase enzyme from binding to the gene and transcribing the structural gene. Such genes are induced by the arrival of an inducer molecule which binds to the repressor protein and rendering it inactive. This allows transcription from the structural gene and the production of a protein.

Other genes are normally active and able to be constantly transcribed, because the repressor protein is produced in an inactive form. On the arrival and binding of the corepressor molecule the complex can act as a functional repressor and block the structural gene by binding at the operator site.

These genes are therefore either inducible or repressible.